Studies I and II: The Prelude. Luke 1:1-56

Springer Contents Part I Prelude

I-11: Optimizing the ART Outcome

Background: The establishment of a high quality ART program requires a multi-disciplinary effort, involvement and commitment of all staff members – team work. It is of vital importance that all aspects of the treatments are taken into consideration and that you already from the start use high international standards to initiate a wellorganised ART program that meets the requirements from patien...

56-month clinical performance of Class I and II resin composite restorations

OBJECTIVE This study evaluated the 56-month clinical performance of Class I and II resin composite restorations. Filtek P60 was compared with Filtek Z250, which are both indicated for posterior restorations but differ in terms of handling characteristics. The null hypothesis tested was that there is no difference in the clinical performance of the two resin composites in posterior teeth. MATE...

Studies of Antimetabolites* Ii. I-acetylpyridine

When 3acetylpyridine (3-AP) is fed to dogs, large amounts of a normal end-product of nicotinic acid metabolism, N’-methylnicotinamide (NMeN), appear in the urine (1). This finding might be interpreted as evidence that 3-AP, acting as an antivitamin, displaces nicotinamide from its nucleotides or prevents its incorporation therein, or, alternatively, that 3-AP is biologically oxidized to nicotin...

Overview of phase I/II pemetrexed studies.

Pemetrexed (Alimta) is an antifolate that is effective in the inhibition of multiple enzyme targets including thymidylate synthase, dihydrofolate reductase, and glycinamide ribonucleotide formyl transferase. The compound has been evaluated in several phase I trials, both as single agent and in combination with other cytotoxic agents. The initial schedule selected for further investigation in ph...